PD-1/CD279/PDCD1抗体

产品货号：

Z36198

中文名称：

PD-1/CD279/PDCD1抗体

英文名称：

Anti-PD-1/CD279/PDCD1 Antibody (Clone#4D6)

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-PD-1/CD279/PDCD1 Antibody (Clone#4D6)
指标别名	CD279;hPD 1;hPD l;PD 1;PD1;PD-1;PD-1/CD279;PDCD1;programmed cell death 1;Protein PD 1;SLEB2
克隆性	Monoclonal
检验物种	human
应用范围	ELISA,WB,IHC,ICC,IF
基因名称	PDCD1
克隆号	4D6
抗体来源	Mouse
抗体类型	IgG1
免疫原	PD-1 antibody was raised against the extracellular domain of human PD-1.
计算分子量	32kDa
成分	PD-1 Antibody is supplied in PBS containing 0.02% sodium azide and 50% glycerol.
纯化方式	PD-1 Antibody is supplied as protein A purified IgG1.
浓度	1mg/mL
产品形态	溶液
保存条件	4℃可保存3个月，-20℃可保存1年。
背景资料	Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC).T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC.PD-1 can bind two different but related ligands,PDL-1 and PDL-2.Upon binding to either of these ligands,signals generated by PD-1 inhibit the activation of the immune response in the absence of "danger signals" such as LPS or other molecules associated with bacteria or other pathogens.Evidence for this is seen in PD-1-null mice who exhibit hyperactivated immune systems and autoimmune diseases.PD-1 is thus one of a growing number of immune checkpoint proteins.
Uniprot ID	Q15116
基因名全称	Programmed cell death 1
蛋白名全称	Programmed cell death 1
推荐稀释比	PD-1 antibody can be used for detection of PD-1 by Western blot at 0.25 ～ 0.5μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

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